Aug 17, 2022 · Mantle cell lymphoma is a subtype of non-Hodgkin lymphoma. It’s called mantle cell lymphoma because it starts in B lymphocytes located in mantle zones of the lymph nodes. Mantle cell lymphoma often begins as a slow-growing (indolent) disease …

Mantle cell lymphoma (MCL) is a type of non-Hodgkin's lymphoma, comprising about 6% of cases. [1] [2] It is named for the mantle zone of the lymph nodes where it develops. [3] [4] The term 'mantle cell lymphoma' was first adopted by Raffeld and Jaffe in 1991. [5]

May 1, 2023 · Mantle cell lymphoma is a cancer of white blood cells, which help your body fight infections. You may hear your doctor call your condition a type of "non-Hodgkin's lymphoma."

Sep 28, 2020 · In many cases, a tumor is the first obvious mantle cell lymphoma symptom. Tumors may appear anywhere you have lymph nodes, though they’re often found in the neck, armpit or groin. “Most people don’t feel their armpit or groin very often, so they may not notice a small bump,” Wang says.

Jan 6, 2025 · Mantle cell lymphoma is a subtype of non-Hodgkin lymphoma and accounts for approximately 5 to 6% of all non-Hodgkin lymphoma cases in the United States. It occurs when B-cells abnormally and rapidly proliferate and expand within the mantle zone of a lymph node.

Mantle Cell lymphoma (MCL) is an aggressive, rare form of non-Hodgkin lymphoma (NHL) that arises from cells originating in the “mantle zone.” The mantle zone is the outer ring of small lymphocytes surrounding the center of a lymphatic nodule.

Jul 28, 2023 · Mantle cell lymphoma (MCL) is a rare subtype of B-cell non-Hodgkin lymphomas (NHLs) usually identified by a translocation of the CCND1 gene. The variety of morphologic variants may make this a challenging diagnosis, although most cases are uncomplicated.

Mantle cell lymphoma is one of more than 60 subtypes of non-Hodgkin lymphoma. It takes its name from where it begins — in the mantle zone of lymph nodes. This is a ring of cells surrounding small structures within lymph nodes called germinal centers.

Jun 5, 2024 · MCL is a B-cell lymphoma that develops from malignant B-lymphocytes within a region of the lymph node known as the mantle zone. It affects mostly men who are usually 60 to 70 years old. Approximately one out of 200,000 individuals per year are diagnosed with MCL.

Nov 9, 2024 · This perspective article by Drs. Pileri and Falini examines the diagnosis and bio-pathology of mantle cell lymphoma in the light of the criteria of the WHO Classification and recent reports. See related articles on pages 1555, 1563 and 1595.