Jun 26, 2024 · Clinical trials are a type of research that studies new tests and treatments and evaluates their effects on human health outcomes. People volunteer to take part in clinical trials to test medical interventions including drugs, cells and other biological products, surgical procedures, radiological procedures, devices, behavioural treatments and ...

Dec 8, 2020 · When the results of all these clinical trials are available, a series of steps is required, including reviews of efficacy and safety for regulatory and public health policy approvals. Officials in each country closely review the study data …

Ethical frameworks that support inclusion While the exclusion of pregnant persons from biomedical research has reduced pregnancy-specific risk in research contexts, it has not eliminated risk. Rather, it has “shifted the burden of potential risk around drug safety from the clinical trial setting, where safety outcomes are carefully monitored, to the real-world clinical care setting, where ...

Aug 10, 2021 · Vaccines go through various phases of development and testing – there are usually three phases to clinical trials, with the last one designed to assess the ability of the product to protect against disease, which is called efficacy. All phases assess safety.

Sep 25, 2024 · This guidance updates and adapts the previous work of the World Health Organization (WHO) on research capacity for the context of well-designed and well-implemented clinical trials as framed in resolution WHA75.8 (2022). It aims to enhance clinical research efficiency, minimize research waste and provide guidance on sustained clinical trials that are always functional and active for endemic ...

The number of trials listed in the WHO International Clinical Trials Registry Platform is reported by year, country, WHO region and income group

Clinical trials registries: the International Clinical Trials Registry Platform (ICTRP), clinicaltrials.gov. Status of health products in the pipeline from the WHO Global Observatory on Health Research and Development, based on Springer Nature AdisInsight data source.

Jan 16, 2020 · For the purposes of registration, a clinical trial is any research study that prospectively assigns human participants or groups of humans to one or more health-related interventions to evaluate the effects on health outcomes. Clinical trials may also be referred to as interventional trials.

The platform has a searchable portal: International Clinical Trials Registry Platform (ICTRP) search portal clinicaltrials.gov ClinicalTrials.gov is a registry and results database of privately and publicly funded clinical studies conducted around the world. The resource is provided by the U.S. National Library of Medicine.

Sep 25, 2024 · The World Health Organization (WHO) today released guidance to improve the design, conduct and oversight of clinical trials in countries of all income levels. This guidance aims to support stronger country-led research and development (R&D) ecosystems to advance health science so that new, safe and effective health interventions can be made more accessible and affordable globally for people ...