Tridecanoic acid (C13) is a rare, odd-chain saturated fatty acid produced mainly by gut and rumen microbes, entering ...

a, The TCA cycle (green) and the asct modification (pink).b, Restoration of TCA cycle function by asct from diverse bacteria (labelled 1–6) in E. coli succinyl-CoA synthetase (SCS) knockouts ...

The study explored the role of succinyl-CoA synthetase (SCS) through a series of experiments involving the construction of plasmids through polymerase chain reaction (PCR) amplification ...

As explained in an in-depth review, this inactivation stops your body from converting homocysteine into methionine or methylmalonyl-CoA to succinyl-CoA, which are essential for producing and ...

The enzyme acetyl-CoA synthetase 2 turns on memory-building genes within the nuclei of hippocampal neurons. A protein from Helicobacter pylori inhibits amyloid formation in both microbes and humans, ...

In these disorders, the conversion of ketone bodies to acetyl CoA becomes rate limiting. As a consequence, ketone production is uncoupled from consumption, leading to profound metabolic acidosis.