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In the case of Strand’s lead anticancer treatment, the mRNA sequence contains elements that only switch translation on in the presence of microRNA biomarkers around tumors.
Strand’s therapy uses mRNA to make an inflammatory protein called interleukin-12, or IL-12, that causes immune cells to spring into action and unleash a cascade of events that kill cancer cells ...
What's the difference between mRNA and pre-mRNA? It's all about splicing of introns. See how one RNA sequence can exist in nearly 40,000 different forms.
Lipids formulated with a bioreducible linker form the wall of nanoparticles encapsulating the mRNA of Cas9 plus sgRNA. Upon entering the cell, in vitro or in vivo, the linkers are broken and the ...
Sugar: In DNA, the sugar is deoxyribose, while in RNA, it is ribose.The sugar forms the backbone of the nucleic acid strand. Phosphate Group: The phosphate group is attached to the sugar and helps ...