A new artificial intelligence model can improve the process of drug and vaccine discovery by predicting how efficiently ...

Scientists at Tel Aviv University and the Israel Institute for Biological Research have developed the first mRNA vaccine ...

DNA makes RNA, RNA makes protein, protein makes phenotype—was the guiding framework for understanding inheritance and disease. This model explained classic Mendelian traits, such as how single DNA ...

Now, mRNA vaccines can be quickly created against different antigenic targets by changing the mRNA sequence, and companies are looking beyond COVID-19 at other infectious diseases, including ...

Moderna’s foundation in mRNA technology has positioned it as a leader in the development of novel therapeutics and vaccines. The company’s breakthrough success with its COVID-19 vaccine ...

mRNA therapeutics are complex to design and manufacture. From mRNA sequence engineering to fill-and-finish, mRNA therapeutic development requires precise, consistent, and exacting quality analysis.

Founded in 2020, RIBOPRO develops and manufactures high-quality mRNA and LNPs while offering innovative solutions, including sequence optimization algorithms and a proprietary LNP platform.

For example, they have characterized the transcriptome (mRNA, lncRNA, and miRNA) of aortas in an atherosclerosis mouse model, both during disease progression and after regression following treatment.

These tools are instrumental in identifying conserved regions and potential immunogenic epitopes within the mRNA sequences. Following alignment, assembly algorithms reconstruct full-length mRNA ...

Scientists have discovered that tRNAs can determine how long mRNAs exist in a cell, causing some messages to be stabilized and translated into more protein, while directing others to be degraded and ...

The analysis of the RNA-seq and Ribo-seq data could be more in-depth, however, the authors were able to show with certainty that some transcripts containing known repetitive sequences or polybasic ...