Subtle differences in an mRNA sequence enables a ribosome to produce more or less of a certain protein. A new AI model called ...

Researchers aimed to develop tools to create novel mRNA sequences — ones that code for viral proteins, for example — in the lab, and then introduce those mRNA molecules into cells. The cells would ...

For example, the company’s MRT5005 delivers an mRNA encoding a fully functional cystic fibrosis conductance regulator to the lung. It is currently in Phase I/II trials.

What’s more, the same basic ingredients can be used each time, adding only one unique component—an mRNA sequence—to produce the required protein. ... For example, about 90 percent of ...

Scientists at Tel Aviv University and the Israel Institute for Biological Research have developed the first mRNA vaccine ...

Two examples of epitope-based vaccines for SARS-CoV-2 are UB-612 and NVX-CoV2373. Scientists have developed several epitope prediction models, which can be categorized into sequence-based and ...

Messenger RNA (mRNA) are biological molecules that transfer the information coded by genes in the nucleus to the cytoplasm for protein synthesis by ribosomes. mRNA sequences can be designed to ...

The mRNA vaccines now in use are based on early SARS-CoV-2 strains and include a genetic sequence from the "original" spike protein. But like any virus, SARS-CoV-2 is constantly mutating. Some ...

LNPs — tiny, fatty droplets that can carry mRNA into cells — have become more prevalent after they were used as the basis of the COVID-19 vaccines to deliver mRNA to immune cells inside the arm. LNPs ...

Protein sequencing refers to methods for determining the amino acid sequence of proteins (or peptides) and analysis of the sequence, for example to infer protein conformation. Techniques include ...