No longer a mere assistant who carries out the commands of DNA, RNA takes the lead in emerging therapeutics.

To estimate the readthrough efficiency of the AGO1 stop codon, these authors used a dual-luciferase reporter system in which AGO1-F-luc and R-luc were translated from separate mRNAs. AGO1-F-luc ...

Advances in de novo synthesis of DNA and computational gene design methods make possible the customization of genes by direct manipulation of features such as codon bias and mRNA secondary structure.

Professor Hirohide Saito and his research team have developed a new microRNA-responsive hybrid mRNA switch, enabling precise, ...

Researchers from Tel Aviv University and the Israel Institute for Biological Research in Ness Ziona have used the platform ...

To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian ...

The elephant vaccine closely resembles other mRNA vaccines made for humans. mRNA packed in lipid nanoparticles carries ...

Compared to the standard shot, the mRNA vaccine had an overall vaccine efficacy that was 26.6 percent higher, and 27.4 ...

Researchers have described proteins that they say are among the most ancient ever sequenced. Two teams, which analysed ...

Scientists have discovered the internal shape of tiny drug-delivery particles – called lipid nanoparticles – has a big impact ...

The best sequence has an affinity of approximately 1.7 nM and seven of the isolated binders can inhibit the virus replication from 11- to 5900-fold.