In addition, EB613 significantly increased BMD at each measured skeletal site as compared with baseline and placebo. To explore the dual actions of EB613 further, 3D-DXA analysis was performed using 3 ...

Taste, pain, or response to stress -- nearly all essential functions in the human body are regulated by molecular switches called G protein-coupled receptors (GPCRs). Researchers have uncovered ...

Authors' Disclosures of Potential Conflicts of Interest Second-Line Endocrine Therapy With or Without Palbociclib Rechallenge in Patients With Hormone Receptor–Positive/Human Epidermal Growth Factor ...

FcRn protects IgG and albumin from catabolism, transports IgG across the placenta, and regulates IgG function. Blocking or augmenting FcRn can decrease autoimmune antibodies and enhance drug delivery.

Traditional SLT involves using a laser to manipulate the eye's trabecular meshwork, located around the base of the cornea, which acts as the natural drain for the eyeball's aqueous humor. Glaucoma is ...

Although TRPV4‐driven RhoA signaling activation has been observed in fibroblasts and trabecular meshwork cells, its role in VICs remains unexplored in the context of AVS.

High-resolution microscopic images of T cells that have been engineered with TGF-beta SNIPRs (shown in red) as they bind to TGF-beta (shown in green). The SNIPRs activate once the receptors fold into ...

Further, and based on ligand and receptor expression patterns, we document key interactions between SECs and cells of the adjacent trabecular meshwork (TM) drainage tissue. Also, we present cell type ...

They work by improving the outflow of the trabecular meshwork. They act on the rho-associated kinase pathway, which plays a role in regulating pressure in the eye.

Trabecular meshwork pigmentation levels are not associated with success in a combined phacoemulsification and minimally invasive glaucoma surgery (phaco/MIGS) procedure, according to a study published ...

Researchers have traced the origin and evolutionary trajectory of plant immune receptors. Their discovery will make it easier to identify immune receptor genes from genomic information and could ...