Both RNA-Seq and microarrays provide accurate relative measurements of lncRNAs but neither method gives absolute measurements 1 because each introduces gene-specific biases, for example due to ...

Most of the mammalian genome is transcribed producing non-coding RNA. The RIKEN FANTOM projects have earlier demonstrated that the largest output of the genome is constituted by non-coding RNAs.

The overwhelming majority of genes in the human genome encode RNA molecules that are not translated into proteins. These RNA molecules are named non-coding RNAs (ncRNAs). ncRNAs play a crucial ...

RNA vaccines are a new class of vaccines that are composed of an mRNA sequence coding for a pathogen-specific protein (antigen). Once expressed in the body, the target antigen is recognized by the ...

Researchers discover high levels of non-coding RNAs in testes, suggesting new roles in sperm function and evolution Jul 30, 2024 New study discovers tiny target on RNA to short-circuit inflammation ...

One such non-coding RNA is 4.5SH, found only in small rodents like mice and rats. The 4.5SH gene forms a large cluster of tandem repeats, short lengths of DNA repeated multiple times in a gene ...

By detecting both noncoding and coding RNA with COMPLETE-seq, the researchers were able to increase the biological signals available, resulting in a more sensitive diagnostic test. “When we trained ...

TORINO, Italy--(BUSINESS WIRE)--Resalis Therapeutics today announced its completion of the seed financing round of €10 million to establish a non-coding RNA (ncRNA)-based therapeutic approach ...

Researchers have now mapped lncRNA (long non-coding RNA molecules) in human skin wounds in tissue samples from Karolinska University Hospital, identifying a key regulator in wound healing.

Kim’s lab developed an RNA liquid biopsy platform that detects both protein-coding RNA and RNA dark matter in the blood, and showed that this new approach significantly improves the performance of ...

Non-coding antisense RNA can be used to stimulate protein production Date: October 16, 2012 Source: RIKEN Summary: While studying Parkinson's disease, an international research group made a ...