Not only can transposable elements be useful, but new evidence shows they may have been powerfully linked to primate evolution.

This AI system can analyze up to one million DNA letters at once, predicting how tiny changes in noncoding regions trigger ...

DNA molecules contain coding regions—the genes that code for proteins—and non-coding regions that are involved in the mechanisms that regulate or organize the genome.

It was once thought that non-coding regions were effectively “junk” DNA.1 Using very different technologies, two new studies have added further evidence to an already large pile showing that ...

Our present study is the first comprehensive analysis of lncRNA associated DNA methylation change in pan-cancer wide. Our work sheds new light on the complex interaction between lncRNAs and protein ...

Scientists at St. Jude Children’s Research Hospital have discovered non-coding genetic variants contributing to chemotherapy resistance in acute lymphoblastic leukemia.

Non-coding DNA variants contribute to acute lymphoblastic leukemia (ALL) chemotherapy resistance. Explore new technology used in the St. Jude-led discovery.

The protein HMCES forms covalent crosslinks with abasic sites in ssDNA to prevent the formation of toxic dsDNA breaks. This study reports a non‐proteolytic release mechanism that restricts formation ...

The genetic sequences under investigation included nearly 20,000 genes that encode information about how to make proteins, as well as 350,000 regulatory sequences composed of non-coding DNA, which ...

Scientists have found that non-coding 'junk' DNA, far from being harmless and inert, could potentially contribute to the development of cancer.