June 10, 2024 — Scientists have grown 'mini-guts' in the lab to help understand Crohn's disease, showing that 'switches' that modify DNA in gut cells play an ... Major Cause of Inflammatory ...

Upadacitinib induction therapy provides steroid-free clinical remission in over 50% of patients with Crohn's disease who do not respond to conventional treatment and has an acceptable safety profile.