Early data suggest personalized neoantigen vaccines activate the immune system and sustain tumor control in some patients with kidney cancer.

Vaccines have had a major impact on the control of infectious disease, most recently by helping to combat the COVID-19 pandemic. Prophylactic cancer vaccines have prevented several malignancies by ...

Toward a Computable Phenotype for Determining Eligibility of Lung Cancer Screening Using Electronic Health Records Accurate human leukocyte antigen (HLA) typing is an essential step for designing ...

Birmingham's Queen Elizabeth Hospital is taking part in a trial of a groundbreaking cancer vaccine.

Breakthrough vaccine targets pancreatic cancer cells, showing promise in preclinical trials and paving the way for human testing.

Now, researchers at Case Western Reserve University and Cleveland Clinic are developing vaccines targeting pancreatic cancer that could eliminate the disease, leaving a patient cancer-free.

Researchers say the vaccine, developed by Anixa Biosciences and funded by the Department of Defense, could eliminate breast cancer - which one out of eight women will get in her life - by 2030.

Traditional neoantigen prediction methods primarily rely on HLA-peptide binding databases, often producing false positives. This challenge highlights the need for improved strategies to identify truly ...

Using T cell receptor sequencing on both functionally expanded T cells and neoantigen-loaded tetramer-sorted T cells, we identified tumor antigen-specific T cell receptors,” write the investigators.