Baxdrostat is a highly selective, second-generation, nonimidazole aldosterone synthase inhibitor; 100 times less baxdrostat is required for inhibition of aldosterone synthesis than for inhibition of ...

Sweetness is central to the appeal of citrus fruit, but the molecular story behind that flavor has long remained untold.

Chemists use a cycle of enzymatic oxidation and chemical reduction to drive molecular rotation ...

Scientists have successfully restored hearing in animal models of ENPP1 deficiency, a genetic disease in which individuals lack an enzyme essential for bone and blood vessel health. The rare ...

AstraZeneca announced that baxdrostat, a selective aldosterone synthase inhibitor, met its primary and all secondary endpoints in the BaxHTN Phase III trial, effectively lowering blood pressure ...

High-resolution cryo-electron microscopy makes it possible to study complex enzymatic processes in detail. With this method, a research team of the University of Potsdam and Humboldt-Universität ...

Cannabidiol within the range consumers are taking with unregulated products linked to increase in liver enzymes.

The enzyme AMPD1 plays a key role in muscle energy production and normal muscular function. Loss of AMPD1 activity due to genetic mutations is the most common cause of metabolic myopathy in Europeans, ...