Successive enzymatic reactions by a number of enzymes are generally required to ... Here the authors introduce a modular polyketide synthase platform for the efficient production of these compounds.

A new study has unveiled the intricate genetic mechanisms that regulate theanine accumulation in tea plants—a key determinant ...

AceLink is advancing a small-molecule treatment option for Fabry disease, which could provide a more convenient alternative ...

Hypertension is a major global health issue. Aldosterone synthase inhibitors (ASIs) have emerged as a promising therapeutic strategy for blood pressure control. A thorough search of the MEDLINE and ...

The Phase Ib trial is set to test a gene therapy designed to target a rare disorder that causes muscle and respiratory failure.

Elevated liver enzymes can occur for many reasons. Most often, elevated liver enzymes are temporary and resolve on their own without treatment. Occasionally, elevated liver enzymes require additional ...

CCM Biosciences has developed groundbreaking compounds that activate the enzyme SIRT3, potentially reversing age-related cellular decline. These first-in-class drugs outperform existing treatments and ...

This enzyme could be transformative for industry, it not only speeds up a crucial class of chemical transformation, but does so with remarkable precision, even when working with challenging chemical ...

Temperature affects enzyme-catalysed reactions by influencing the rate at which they occur. For a reaction to occur between an enzyme and substrate the two molecules need to collide. At lower ...