Baxdrostat is a highly selective, second-generation, nonimidazole aldosterone synthase inhibitor; 100 times less baxdrostat ...

Chemists use a cycle of enzymatic oxidation and chemical reduction to drive molecular rotation ...

AstraZeneca announced that baxdrostat, a selective aldosterone synthase inhibitor, met its primary and all secondary ...

High-resolution cryo-electron microscopy makes it possible to study complex enzymatic processes in detail. With this method, a research team of the University of Potsdam and Humboldt-Universität ...

An international research team led by CIC bioGUNE has advanced understanding of classical homocystinuria, a rare genetic disorder that impairs the breakdown of homocysteine, causing systemic health ...

The researchers also found that nitric oxide synthase (NOS), another enzyme linked to inflammation, worsens the effects of IDO1.

ATP synthase is a critical enzyme in the synthesis of ATP for M. tuberculosis. [16, 23] Binding of TMC207 to the oligomeric and proteolipic subunit c of mycobacterial ATP synthase leads to ...

Highly accurate discovery of terpene synthases powered by machine learning - pluskal-lab/EnzymeExplorer ...

Mineralys Therapeutics’ aldosterone synthase inhibitor has chalked up a third clinical win in recent months, demonstrating once again its potential to reduce blood pressure in patients with ...

Acquisition is Strong Strategic Fit for BioMarin, Adding INZ-701, a Phase 3 Enzyme Replacement Therapy Being Developed for Treatment of ENPP1 Deficiency First Pivotal Data Readout in Children Expected ...

Artistic rendering of cellulose biosynthesis with zoomed in view. Individual cellulose chains (dark brown) are synthesized by plasma membrane-bound (purple) cellulose synthase enzyme complexes (cream) ...

Mineralys Therapeutics enjoyed a 45% stock bump after its aldosterone synthase inhibitor chalked up wins in two types of hypertension.