A new tool called PHOTON, developed by scientists at UT Southwestern Medical Center, can identify RNA molecules at their native locations within cells—providing valuable clues to where different RNA ...

New method maps RNA in cells at native locations, revealing spatial responses to signals and offering insight into disease ...

Modifications in proteins after they are synthesized (post-translational) are changes that play a fundamental role in cell ...

The tumor suppressor p53 is a transcription factor that controls the expression of hundreds of genes. Emerging evidence suggests that the p53-induced RNA-binding protein ZMAT3 is a key splicing ...

This valuable study identifies asymmetric dimethylarginine (ADMA) histones as potential determinants of the initial genomic binding of Rhino, a Drosophila-specific chromatin protein essential for ...

One class of functionally important RNA is repeating transcripts that cause disease through various mechanisms. For example, expanded CAG repeats can cause Huntington’s and other disease through ...

We introduce a melded chemical and computational approach for probing and modeling higher-order intramolecular tertiary interactions in RNA. 2′-Hydroxyl molecular interference (HMX) identifies ...