Iowa State is joining the loaded Players Era Festival in Las Vegas in November. The Cyclones face quality opponents St. John's, Creighton to start.

Newly renamed as Casey's Center, the former Wells Fargo Arena has been making Des Moines memories for 20 years this month. Here's a look back.

Fye The Catholic Messenger A larger population base that draws many more worshippers led the Byzantine Catholic Outreach ...Read More ...

Des Moines police arrested 44-year-old Mario Ricardo Campos, who allegedly fled from a deadly crash. Police say Campos was impaired.

DES MOINES, Iowa — Des Moines police are investigating after a body was recovered from the Des Moines River Friday night.

Nitrate levels remain elevated in the Des Moines and Raccoon rivers, two of the drinking water sources for Central Iowa Water Works' 600,000 customers. The regional utility recently shared how it ...

Modeled partly on the Dickeyville Grotto, Madeline Buol spent 15 years building a backyard shrine that is now on view at the John Michael Kohler Arts Center.

Offseason winner? Iowa basketball makes a case. How Ben McCollum got it done. Tyler Tachman Des Moines Register 0:04 11:03 ...

Des Moines University’s state-of-the-art health simulation center recently became one of only eight centers worldwide to be accredited for its human simulation. Center director Kimberly ...

Sign-ups are open to attend President Donald Trump’s speech at the Iowa State Fairgrounds July 3, the kickoff event for what he says will be a yearlong celebration leading up to July 4, 2026.