The field of spatial transcriptomics utilizes technologies that map gene expression data to specific cellular locations within tissues.. While traditional RNA sequencing methods generate quantitative ...

More information: Yitao Yang et al, STAIG: Spatial transcriptomics analysis via image-aided graph contrastive learning for domain exploration and alignment-free integration, Nature Communications ...

Spatial data gives valuable context to the flood of genomic information that has emerged since the human genome was sequenced. In this infographic, we explore the milestones that led to the spatial ...

Spatial transcriptomics (ST) emerges as a pivotal technique for cataloging gene expression across tissue sections while retaining crucial locational data. Traditional methodologies, encompassing ...

Spatial transcriptomics has added an essential dimension to our understanding of musculoskeletal biology. It enables us to pinpoint where genes are active within the intact tissue environment, ...

Spatial transcriptomics is a new tool that may prove key to increasing our understanding of tissues and the cellular processes at work in a 3D space. This article describes the basic principles of ...

However, "previous spatial transcriptomics data for Alzheimer's have not truly resolved single-cell data," Peng said. "Existing methods result in a low-resolution output, often clustering multiple ...

Previous iterations of spatial transcriptomics have been used to map what happens around amyloid plaques, and to define which subtype of dopaminergic neurons are prone to perishing in people with ...

Nova-ST, a new spatial transcriptomics technique, has been introduced by researchers based at Vlaams Instituut voor Biotechnologie (VIB), Katholieke Universiteit (KU) Leuven. According to the ...

K nowing the location of a gene within intact tissue or a single cell allows scientists to unlock unknown cellular functions. This information is often lost in most genetic sequencing techniques, but ...

Single-Cell Spatial Transcriptomics with Cleavable Fluorescent Probes In this webinar, Jia Guo discusses the basics of in situ hybridization and how to use novel fluorescent probes for ultra-sensitive ...

Spatial transcriptomics techniques, which map gene activity in intact tissues, often face challenges in accurately identifying distinct tissue regions. Now, researchers from Japan have developed ...