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Every year, two to four million tons of sodium sulfate is extracted as a manufacturing byproduct. Common disposal pathways include placement in solid waste landfills, subsurface disposal, or the ocean ...
This review provides a comprehensive summary of the synthesis of the second-generation antifungal agent isavuconazole, its water-soluble prodrug, isavuconazonium, and the prodrug side chain.
Herein, we report decarboxylative sulfonylation involving α-N-phthalimido-oxy isobutyrate (NPIB) as a radical precursor. We successfully developed different NPIBs from N-hydroxyphthalimide and alkyl ...