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The requirement for the temporal linkage of actin turnover and transcription necessitates signal transduction mechanisms that communicate the cytoplasmic actin polymerization status to the nuclear ...

The development of reliable abstractions, models, and characterizations of biochemical communication channels that propagate information from/to biological cells is one of the first challenges for the ...

Sensing stress within the endoplasmic reticulum (ER), the ER transmembrane protein IRE1α initiates a signal transduction pathway to restore homeostasis.

Visualization of biological mechanisms by means of pathway graphs is necessary to better understand the often complex underlying system. Manual layout of such pathways or maps of knowledge is a ...