Furthermore, when the effects of lenvatinib on signal transduction pathways were analyzed in six thyroid cancer cell lines, enhancement of EGFR phosphorylation was observed in all the cell lines ...

The MAP Kinase signal transduction pathway plays an important role in embryonic development as well as in differentiation, growth and programmed cell death of human cells.

PIP2 is an important phosphoinositide that is present in around 1% of the plasma membrane. It is also involved in signal transduction of intracellular and extracellular components. There are two ...

In neurons, mitogen-activated protein kinase (MAPK) regulates a variety of signal transduction pathways, including those involved in long-term memory and survival, so anything that modulates MAPK ...

Background: With the advent of molecularly targeted therapy in cancer care, identification of target population for target drug is of utmost importance. Gastric cancer has not been extensively ...