Reconstructing gene regulatory networks (GRNs) using single-cell RNA sequencing (scRNA-seq) data holds great promise for unraveling cellular fate development and heterogeneity. While numerous ...

Gabriella Ngang, of Farmington Hills, is one of three in Michigan to take part in a clinical trial of a new sickle cell disease gene-editing therapy.

Gene therapy for sickle cell disease may help improve a major contributing factor to stroke risk in patients, reports a new study from St. Jude Children's Research Hospital.

Gene therapy for sickle cell disease may help improve a major contributing factor to stroke risk in patients, reports a new study from St. Jude Children's Research Hospital. Many people with ...

Scientists at St. Jude Children’s Research Hospital found that patients with sickle cell disease who received gene therapy experienced a return to normal blood flow in the brain.

Learn about the clinical and pathological features of stroke in individuals with sickle cell disease and strategies for prevention and management of stroke in this patient population.

The Company's lead asset, CLY-124, is designed to treat sickle cell disease through a novel Globin-Switching mechanism and is under evaluation in a Phase 1 clinical study.