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Chronic inflammation is involved in the development of abdominal aortic aneurysm (AAA). A tertiary lymphoid structure (TLS) within vascular lesions has recently been focused on for its role in ...

Evidence suggests that RNA aids nucleation of these pathological aggregates; however, the mechanism has not been investigated at the level of atomic structure. Here, we present the 3.4-Å resolution ...

RNA sequences encode structures that impact protein production and other cellular processes. Misfolded RNAs can also potentiate disease, but a complete picture is lacking. To establish more ...

DNA contains the sugar deoxyribose, while RNA contains the sugar ribose, which has one more oxygen atom than deoxyribose, and DNA is typically double-stranded, forming a double helix structure.

Reduction and depurination of DMS-modified RNA enables detection of N7G-DMS adducts with misincorporations. (A) Strategy for the misincorporation detection of N7G methylation. N7-methylated G is ...

For detailed explanation of settings used for each RNA secondary structure modeling approach see METHODS. Incorporation of experimental data improved Spinach secondary structure modeling; however, all ...

Integrated multi-omics analysis reveals immune landscape of tertiary lymphoid structure in retroperitoneal liposarcoma.. If you have the appropriate software installed, you can download article ...

Google DeepMind launches AlphaFold 3, the next generation of its molecular structure prediction model that can aid drug discovery and other molecular developments.