Skeletal muscle tissue provides mechanical force for locomotion of all vertebrate animals. It is prone to damage from acute physical trauma and physiological stress. To cope with this, it possesses a ...

Collectively, these data indicate that while some embryonic Scx + cells can incorporate into myofibers, adult Scx + cells contribute to skeletal muscle architecture and repair/regenerative process in ...

Genetic mouse models combined with single-cell RNA sequencing reveal the essential role of SRSF2 in directing MyoD progenitors to distinct skeletal muscle domains and controlling their differentiation ...

Satellite cells are skeletal muscle stem cells that contribute to postnatal muscle growth, and they endow skeletal muscle with the ability to regenerate after a severe injury. Here we discover that ...

Apell, H.J., Forsberg, S. and Hollmann, W. (1988) Satellite cell activation in human skeletal muscle after training Evidence for muscle fiber neoformation. The International Journal of Sports Medicine ...

These target genes help explain the muscle regeneration defects of ScxcKO, and are not overlapping with Scx-target genes identified in tendon development. Together with a recent finding of a ...

Our skeletal muscles, which link to bones and enable us to move, have a remarkable ability to regenerate after they've suffered an injury. Scientists have now developed a cutting edge microscopy tool ...

BACKGROUND: We hypothesized that transcriptomic profiling of muscle satellite cells in peripheral artery disease (PAD) would identify damage-related pathways contributing to skeletal muscle myopathy.

In a new study, stopping skeletal-muscle cancer cells from making a specific protein forced them to turn into healthy muscle cells.