Article Published: 25 July 2016 Skp is a multivalent chaperone of outer-membrane proteins Bob Schiffrin, Antonio N Calabrese, Paul W A Devine, Sarah A Harris, Alison E Ashcroft, David J Brockwell ...

AFM and NMR are used to observe how the chaperones Skp and SurA work to fold a β-barrel outer-membrane protein, FhuA. Skp maintains FhuA in an unfolded state, and Sur A facilitates its folding.