Restriction fragment length polymorphism (RFLP) is a technique invented in 1984 by the English scientist Alec Jeffreys during research into hereditary diseases. It is used for the analysis of ...

A novel method called “multiplex-terminal restriction fragment length polymorphism (M-TRFLP)” has been recently developed which can be used for simultaneous analysis of the community ...

In 1980, a landmark paper described restriction fragment length polymorphism (RFLP), a method predateding high volume DNA sequencing, that could be used to identify disease-causing genes. Ray ...

In the early 1980s, genetic typing was in its infancy, with researchers using restriction fragment length polymorphisms (RFLPs) to detect variations in DNA sequences. 1 This method, which employed ...

Nuclear DNA restriction fragment polymorphisms are being found that successfully distinguish African and European bees as well as hybrids between the two. Beyond identification for regulatory purposes ...

DNA fragments are initially generated with restriction enzymes and separated by size in a process called gel electrophoresis. Alkaline is then used to denature the doubled-stranded DNA, forming ...