Inside each cell of the human body are proteins that control which genes are expressed at the right place and time. However, intriguingly, many of the most important proteins involved in gene ...

Most genes are ancient and shared across species. But a small subset of genes are relative newcomers, spontaneously emerging from stretches of DNA that once encoded nothing at all.

CRISPR construct to genetically ablate the GABA transporter GAT3 in the mouse visual cortex, with effects on population-level neuronal activity. This work is important, as it sheds light on how GAT3 ...

Glycine administration inhibits HBV cccDNA expression and enhances hepatocyte proliferation.Glycine administration triggers hepatocyte regeneration through activation of mTORC1 signalling and its ...

This suggests that Telomir-1 may help restore healthy gene regulation and reset the body's epigenetic aging clock, reducing the risk of dysfunction in key biological systems. 2. Telomere Elongation - ...

A new study shows AI can design synthetic DNA to precisely control gene expression in healthy mammalian cells. The model created custom enhancers from scratch, enabling selective gene activation or ...

Media Resources Genetic regulation of gene expression across multiple tissues in chickens (Nature Genetics) Emily Dooley is a writer with the UC Davis College of Agricultural and Environmental ...

This study provides a vital mechanism proving that IPMK, a key enzyme in the inositol metabolism system, is a major transcriptional activator in the core gene expression network of animal cells.

An international team of researchers has taken an important step toward understanding how gene expression is controlled across the human genome. A new study has comprehensively analyzed “cis ...

Genes are involved in the development of many illnesses, including cancer, which can develop when a mutated gene is expressed, or switches on, or when a tumor-suppressing gene is turned off. The study ...

Scientists have long studied the processes that underlie gene expression and the chemical modifications of histones because of the downstream effects they have on cellular processes.

Some sequences in the genome cause genes to be switched on or off. Until now, each of these gene switches, or so-called enhancers, was thought to have its own place on the DNA. Different enhancers ...