S-337395 is an investigational oral antiviral candidate for RSV infection that inhibits the activity of the L protein, which is essential for virus replication. 1,2 Furthermore, this drug has received ...

RNA plays an important role in this inactivation process. Specifically, Xist RNA, a long noncoding RNA molecule, is responsible for crumpling up one copy of an X chromosome in each female cell.

Dakota Smith was arrested for the preliminary charge of neglect of a dependent, a Level 6 felony, and remains in the Bartholomew County Jail on a 72-hour hold. The investigation is still ongoing ...

The redness, inflammation, and pain of sunburn may stem from damage to RNA, not DNA. “Sunburn damages the DNA, leading to cell death and inflammation. So the textbooks say,” said Assistant ...

This is where DNA and RNA epigenetics come in: a series of mechanisms that act as "markers" on genes, to control their activity without modifying the DNA or RNA sequence itself. Until now ...

Non-Commercial (NC): Only non-commercial uses of the work are permitted. RNA–protein interactions drive and regulate fundamental cellular processes like transcription and translation. Despite being ...

Institute of Quantitative Biology, College of Life Sciences, and School of Physics, Zhejiang University, Hangzhou, Zhejiang 310058, China ...

Scientists design bioluminescent RNA The 'RNA lanterns' promise to reveal secrets of viruses and human memory Date: January 9, 2025 Source: University of California - Irvine Summary: RNA is the ...

Researchers at the Helmholtz Institute for RNA-based Infection Research (HIRI) and the Julius-Maximilians-Universität (JMU) in Würzburg have identified a protein and a group of small ribonucleic ...

It targets subunit PB2, which along with PA and PB1 forms the RNA-dependent RNA polymerase. This enzyme is essential for viral replication in cells by replicating the viral RNA segments and ...

NPH-I acts on the RNA polymerase ternary complex to effect ... The ATPase activity of NPH-I, which is absolutely dependent on single-stranded DNA, is essential for termination 50,51.

and do not require RNA-dependent RNA polymerase (RdRP) or amplification mechanisms. Other loci form small RNAs after the primary transcripts are processed through dsRNA-forming mechanisms that ...