Remdesivir and favipiravir are currently attracting attention as therapeutic agents against COVID-19. These drugs are thought to act on the RNA-dependent RNA polymerase, a protein that replicates ...

RNA-dependent RNA polymerase (RdRp) is a key enzyme for SARS-CoV-2 genomic replication and transcription and, thus, for viral replication.

SARS-CoV-2 spike protein and RNA dependent RNA polymerase as targets for drug and vaccine development Compuscript Ltd The present pandemic has posed a crisis to the economy of the world and the ...

The RNA-dependent RNA polymerase of the novel coronavirus is a complex that includes the small proteins nsp7 and nsp8. Researchers studying SARS-CoV-2, the novel coronavirus that causes ...

In a new study, a team of researchers compared the severity of the SARS-CoV-2 Omicron variant to the Delta variant using the PCR proxy marker of RNA dependent RNA polymerase target delay.

What am I looking at? This is a 3D rendering of an RNA polymerase II enzyme from baker’s yeast, created using actual molecular data to reconstruct its shape and active sites. What looks like a ...

The presence of mechanisms that copy RNA into RNA, typically associated with an enzyme called RNA-dependent RNA polymerase, has only been documented in plants and simple organisms, such as yeast ...

RNA polymerase IV and V Exclusively found in plants, RNA polymerase IV and V are transcription enzymes that evolved as specialized forms of RNA polymerase II 4. Both enzymes produce small interfering ...

Instead of focusing exclusively on the spike protein, COVID-19 vaccines could also attend to another viral protein, the RNA polymerase that coronaviruses use to make copies of themselves.

Ap sites are known to stall DNA-dependent RNA polymerases (RNAPs). RNA polymerase II (Pol II) briefly stalls at these sites before slowly bypassing them. However, how Pol I responds to this form ...