The ability to analyze gene expression at the single-cell level—known as single-cell RNA sequencing (scRNA-seq)—has ...

By tracking the movement of RNA molecules inside the nucleolus using advanced imaging and genomics techniques, the new method ...

A strategy that analyzes the structural properties of RNA could help identify regions that are promising targets for antiviral drugs.

Human DNA contains roughly 3 billion letters of genetic code. However, we understand only a fraction of what this vast ...

Singapore scientists release one of the world’s largest open-access long-read RNA sequencing datasets, paving the way for global advances in disease research and precision medicine.

RNA sequencing has emerged as a powerful supplement to DNA sequencing for Mendelian disease diagnosis, but clinical translation of diagnostic RNA-seq has not been widely achieved. Researchers at ...

Dec 10, 2024 Nanopore direct RNA sequencing identifies cancer 'fingerprint' (Nanowerk News) Different types of cancer have unique molecular ‘fingerprints’ which are detectable in early stages of the ...

In a study of the effects of spaceflight on human physiology, researchers from Weill Cornell Medicine and other institutions performed direct RNA-seq on samples collected from four astronauts at ...

An individual’s genome is identifiable. But datasets of RNA sequences from single cells are like a blurry photocopy of the genome. The sequence numbers are small, the data are noisy, and the ...

Workflow and Bioinformatic Analysis Pipelines of RNC-mRNA Sequencing There are four major steps in the RNC-mRNA sequencing workflow: (1) sample preparation, (2) library preparation, (3) sequencing, ...

Click chemistry–based RNA sequencing captures bursts of transcription A new technique allows scientists to track RNA expression in single cells at the moment genes are transcribed from DNA to RNA.