The heterogeneity of isoform level m 6 A RNA methylation in single cells is unclear. The authors characterize m 6 A at both single-cell and isoform level through ONT long-read sequencing on single ...

In a new paper published in the journal Nature Methods, researchers at UC Santa Cruz introduce the first-ever method for analyzing RNA sequencing data genome-wide using a “pantranscriptome,” which ...

RNA sequencing has emerged as a powerful supplement to DNA sequencing for Mendelian disease diagnosis, but clinical translation of diagnostic RNA-seq has not been widely achieved. Researchers at ...

A new clinical RNA sequencing platform at The Hospital for Sick Children (SickKids) is helping to facilitate research into rare genetic conditions and carve a path for Precision Child Health, a ...

Li S, Tighe SW, Nicolet CM et al. Multi-platform assessment of transcriptome profiling using RNA-seq in the ABRF next-generation sequencing study. Nat. Biotechnol. 32(9), 915-925 (2014); Wang C, Gong ...

It is designed to facilitate single-cell RNA sequencing by eliminating the need for complex, expensive instrumentation and microfluidic consumables. The company launched its first kit in July 2022.

A clinical research team from the University of Hong Kong (HKUMed) has used amniotic fluid cells obtained during 16-24 weeks of pregnancy as a novel sample type for RNA-sequencing in prenatal ...

Nano-tRNAseq is based on nanopore sequencing, a technology that can directly sequence individual RNA molecules by passing them through a small pore. Each of the nucleotides that compose an RNA ...

First, the pipeline identifies which areas of the genome the RNA sequencing data comes from, including the splice sites, and marks those points on the pangenome reference.

SAN DIEGO — An antibody discovery platform revealed more than 60 monoclonal antibodies specific to patients with alpha-gal syndrome, according to a poster presented here. This molecular ...

Click chemistry–based RNA sequencing captures bursts of transcription A new technique allows scientists to track RNA expression in single cells at the moment genes are transcribed from DNA to RNA.