Anillin (ANLN), a mitotic protein that regulates contractile ring assembly, has been reported as an oncoprotein. However, the function of ANLN in cancer cells, especially in the nucleus, has not been ...

DNA transcription is the vital first step needed for switching on our genes. For a gene to be switched on, it must be acted ...

If your genes could set an alarm clock, EZH1 might be the one ringing the bell. A new study has revealed how this ...

Now, researchers used cryoelectron microscopy (cryo-EM) to elucidate the structure of the Nipah virus polymerase complex (the ...

Several types of RNA help regulate gene expression ... and thus can bind those regions to facilitate polymerase recruitment and DNA looping, which brings the transcription machinery into contact with ...

Researchers have now uncovered the 3D structure of the RNA enzyme SAMURI. Their study provides insights into the development of ribozymes and the evolution of catalytically active RNA. Researchers ...

The findings demonstrate that, under certain circumstances, the RNA polymerase (RNAP ... In bacteria, researchers have long known that transcription begins when RNAP clamps onto a DNA strand ...

The current human tissue-based study provides convincing evidence correlating hippocampal expressions of RNA guanine-rich G-quadruplexes with aging and with Alzheimer's Disease presence and severity.

RNA extraction, reverse transcription using InvAR17 primer ... The sequencing libraries were amplified using Q5-DNA polymerase (NEB) and i50X/i70X Illumina indexing primers (IDT). Final libraries were ...

Messenger RNA (mRNA) vaccine manufacture offers a more streamlined approach to translational development since mRNA constructs for F1 and V can be prepared and formulated at GMP and deployed directly.