If your genes could set an alarm clock, EZH1 might be the one ringing the bell. A new study has revealed how this ...

Anillin (ANLN), a mitotic protein that regulates contractile ring assembly, has been reported as an oncoprotein. However, the function of ANLN in cancer cells, especially in the nucleus, has not been ...

Northwestern Medicine investigators have discovered a novel mechanism that recognizes and eliminates "bad" transcriptional elongation enzymes during gene expression, findings that may inform the ...

Protein synthesis is vital for life, translating genetic information from DNA to functional proteins through transcription ...

One of EZH1’s key roles, the researchers discovered, is stabilizing RNA Polymerase II — the enzyme that converts DNA-encoded instructions into RNA intermediaries — in a process known as transcription, ...

The clinical stage was based on the TNM classification system of the UICC,11 and comprised two stage I, three stage II, one stage III, and nine stage IV disease. Total RNA was extracted ... using a ...

Now, researchers used cryoelectron microscopy (cryo-EM) to elucidate the structure of the Nipah virus polymerase complex ... for both transcription and RNA replication and mutations that have ...

Announcing a new publication for Acta Materia Medica journal. Single-cell RNA sequencing (scRNA-seq) data from published datasets were obtained to investigate the expression and dysregulation of ...

Announcing a new publication for Acta Materia Medica journal. Single-cell RNA sequencing (scRNA-seq) data from published datasets were obtained to investigate the expression and dysregulation of ...

How cells respond to mitochondrial DNA (mtDNA) damage is not fully understood. This study uncovers a mechanism of mtDNA ...