A significant percentage of patients with SSc first present with non-RP symptoms — most commonly puffy fingers/hands — and are associated with more severe disease.

Liquid biopsies are tests that detect signs of cancer through a simple blood draw. Unlike traditional biopsies, which require ...

Billions of years ago, a rock crack exuding heat could have brought different biomolecules together to kickstart protein ...

A new study reveals that blocking ribosomal RNA production rewires cancer cell behavior and could help treat genetically ...

The growing incidence of infectious diseases, cancer, and chronic illnesses has substantially increased the demand for ...

Researchers at the Johns Hopkins Kimmel Cancer Center and Department of Radiation Oncology and Molecular Radiation Sciences uncovered a new tumor-suppressive response that could lead to novel ...

The researchers found that using a drug to inhibit RNA Polymerase 1 (Pol 1) - the enzyme responsible for human ribosomal RNA (rRNA) transcription - triggered a unique stress response that rewires ...

Laiho holds patents on RNA polymerase 1 inhibitors, which are managed by The Johns Hopkins University in accordance with its conflict-of-interest policies.

In addition to its newly launched CleanScribe RNA Polymerase, TriLink offers mRNA capping analogs (including the award-winning CleanCap® M6), mRNA raw materials (nucleotides and other IVT enzymes ...

RNA polymerase in action The three stages of transcription involve various functions of RNA polymerase that result in the synthesis of RNA: 1. Initiation begins when RNA polymerase wraps around the ...

AATF/Che-1 RNA polymerase II binding protein overexpression reduces the anti-tumor NK-cell cytotoxicity through activating receptors modulation Matteo Caforio 1 Nicola Tumino 2 Cristina Sorino 3 ...