The researchers found that using a drug to inhibit RNA Polymerase 1 (Pol 1) - the enzyme responsible for human ribosomal RNA (rRNA) transcription - triggered a unique stress response that rewires ...

Researchers at the Johns Hopkins Kimmel Cancer Center and Department of Radiation Oncology and Molecular Radiation Sciences uncovered a new tumor-suppressive response that could lead to novel ...

A new study reveals that blocking ribosomal RNA production rewires cancer cell behavior and could help treat genetically ...

A significant percentage of patients with SSc first present with non-RP symptoms — most commonly puffy fingers/hands — and are associated with more severe disease.

Laiho holds patents on RNA polymerase 1 inhibitors, which are managed by The Johns Hopkins University in accordance with its conflict-of-interest policies.

A breakthrough assay is advancing how researchers observe gene expression in real time. Named QRIVTA (quantitative real-time ...

This study has shown that HSV-1 is an "opportunistic interior designer" of human cells. | Genetics And Genomics ...

Scientists in Spain and China discovered that HSV-1 begins rewriting the architecture of human genes just one hour after ...

New imaging tools reveal how within an hour of infection, the virus begins to alter our chromosomes to kick-start its own replication.

Simon Claringbold picked and ate wild mushrooms from his garden. Days later, he thought he was taking his last breath.