The primary endpoint is objective response rate, with progression-free survival a key secondary endpoint. The study includes a pre-registration step for arm determination by the molecular tumor board.

The RNA inhibitor olpasiran significantly reduces a type of "bad cholesterol" that's associated with a high risk of ...

Breast cancer (BC) is the most common malignancy among females worldwide. Breast cancer is a highly heterogeneous malignant tumor which is constitutive of ...

Anillin (ANLN), a mitotic protein that regulates contractile ring assembly, has been reported as an oncoprotein. However, the function of ANLN in cancer cells, especially in the nucleus, has not been ...

Even if it’s still playing on a movie theater near you, you can watch the BAFTA Award-nominated film Gladiator II at home. Afterwards, you can either cancel the streaming service altogether or ...

Polygon (POL), a prominent Layer-2 scaling solution for Ethereum, has emerged as a key player in the evolving cryptocurrency landscape. Designed to address Ethereum’s scalability issues, Polygon ...

By revealing the nucleolar interactome of RNA Pol II, the authors show the regulation of transcription by TBPL1 and PAF1 within ribosomal DNA’s intergenic spacers ensures baseline ncRNA levels ...

In November, 39% of candidates sitting for the Level II test were successful, down from a 47% pass rate for those who took the test in August and 59% for May test-takers, the CFA Institute said in ...

Pol Pot and his henchmen inflicted unprecedented carnage, genocide, forced labor camps, and sickness, claiming about 2 million lives, or about a third of this country’s population, after seizing ...

Six years after it started, World War II ended in 1945 with Nazi Germany surrendering in May and its leaders going on trial for war crimes in November. - Nazis on trial - Nazi leaders go on trial in ...