Scientists have discovered how a key protein helps maintain strong connections between brain cells that are crucial for ...

A major scientific advance in protein modeling developed by Microsoft Research AI for Science, has been published in Science.

Drug discovery hinges on the accurate prediction of binding affinity between prospective drug molecules and target proteins that influence disease progression, which is financially and computationally ...

Advancements in artificial intelligence (AI) are dramatically transforming the field of protein science, offering powerful ...

We show how this information can be directly included into a protein–ligand docking program to guide the prediction of the complex structures. Agreement between the experimental and back-calculated ...

Participants in a PET study received the tracer, then gave it time to reach the brain. Then they laid in a scanner that took ...

The global protein purification resin market share analysis is poised for transformative growth between 2025 and 2035, driven ...

Here we use cryogenic electron microscopy to determine the structure of TbAQP2 from Trypanosoma brucei, bound to either the substrate glycerol or to the sleeping sickness drugs, pentamidine or ...

A study by the Center for Redox Processes in Biomedicine (Redoxoma) led by Marilene Demasi from the Butantan Institute (São ...

Fit-ligand is a computational algorithm that enables accurate modeling of multiple conformational states of ligands in X-ray crystallography and cryo-electron microscopy (cryo-EM).

Third, complex proteins consisting of several polypeptide chains or requiring certain post-translational modifications may be intrinsically incompatible with display on phage, bacteria, or yeast.