In contrast to AI-driven drug discovery companies like Xaira, Recursion, or DeepMind spinout Isomorphic Labs, which focus on ...

In a new study, Nobel laureate David Baker and colleagues detail new methods for targeting undruggable "disordered" proteins.

A predictive biophysical model that integrates protein-DNA structures and sequences to accurately determine genomic binding sites and affinities of DNA-binding proteins.

image: Actin structure-dependent preferential cooperative binding of cofilin. AD: axial distance; PE: pointed-end; BE: barbed-end. view more Credit: 2024, Ngo, Vu et al. eLife.

The wiggly targets known to scientists as “intrinsically disordered proteins” have for decades eluded capture by custom-made ...

Discover essential antibody purification methods, from affinity chromatography to ion exchange chromatography, for research ...

Proteins are life's molecular workhorses, doing everything from turning sunlight into food to fighting viruses. They are ...

With regard to outputs, only ProteinReDiff produced new protein designs that included protein sequence, protein structure and ligand structure. With regard to performance, redesigned proteins from ...

Retinol-binding protein 3 (RBP3) is a glycoprotein of about 140 kDa, found in the intercellular space of the retina. It plays an important role in the transport of retinoids - molecules essential ...