Like all complex organisms, every human originates from a single cell that multiplies through countless cell divisions.

Scientists have uncovered how a protein helps build and maintain vital brain connections, providing insights into the ...

In this paper, a 3D shape-based approach is presented for the efficient search, retrieval, and classification of protein molecules. The method relies primarily on the geometric 3D structure of the ...

Given the amino-acid sequence or 3D structure of a protein, how much can we predict about its function using just a desktop computer? The recent explosive growth in the volume of sequence data and ...

The tumor suppressor p53 is a transcription factor that controls the expression of hundreds of genes. Emerging evidence suggests that the p53-induced RNA-binding protein ZMAT3 is a key splicing ...

The current methods to control RNA functions in living conditions are limited. The new RNA-controlling strategy presented in this study involves utilizing 5-formylcytidine (f5C)-directed base ...

Star 113 Code Issues Pull requests Making Protein Modeling Accessible to All Biologists protein-function-prediction protein-fitness protein-language-model foundation-models ...

Long-tailed (LT) classification is an unavoidable and challenging problem in the real world. Most existing long-tailed classification methods focus only on solving the class-wise imbalance while ...

Protein redesign is an enzyme engineering strategy that enhances a template enzyme’s properties by introducing mutations. Although the method is broadly employed for enzyme design, finding optimal ...