PTEN functions predominately as a lipid phosphatase, ... Domain structure of PTEN and PTEN-deletion constructs. (d) ... Diagram illustrating the signalling relationship. (c) ...

An international group of researchers led by Carnegie Mellon University physicists Mathias Lösche and Frank Heinrich have established the structure of an important tumor suppressing protein, PTEN.

High levels of a polyubiquinated form of phosphatase and tensin homolog (PTEN) were associated with an almost four-fold higher risk of a 40% decline in kidney function in a cohort of American ...

A hairpin within the PTEN mRNA 3′UTR is responsible for its regulatory function. (A) Diagram of the secondary structure of PTEN 3′UTR, including PTEN-sh and PTEN-non-sh, analyzed by using ...