Repressed but ready to go: How bivalency holds developmental genes in a poised state for expression
As well as being essential in the precise packaging of DNA into the space of the nucleus, histone proteins are also the site ...
Phys.org21d
How HIV cracks the lock to the cell nucleus
Nuclear pore complexes are the guardians of the human genome that is packaged into the nucleus of all cells. They form selective channels through the envelope of the nucleus and connect its ...
EurekAlert!25d
Study finds surprising way that genetic mutation causes Huntington’s disease, transforming understanding of the disorder
image: Histological staining of the caudate nucleus from a person with Huntington's disease. view more Credit: McLean Hospital’s Harvard Brain Tissue Resource Center / NIH NeuroBioBank ...
Medical Xpress25d
Surprising way that genetic mutation causes Huntington's disease changes understanding of the disorder
Histological staining of the caudate nucleus from a person with Huntington's disease. Credit: McLean Hospital's Harvard Brain Tissue Resource Center / NIH NeuroBioBank ...
The New York Times26d
The Secret to Keeping My Toilet Stain-Free Is in My Kitchen
I tried scrubbing the rim of the toilet with my usual Method Antibacterial Toilet Bowl Cleaner, but it did next to nothing for the stains. Then I bought some Clorox Toilet Bowl Cleaner with bleach ...
Daily Mail28d
Which drink stains your teeth more - Coke, coffee or red wine? Dentist's experiment reveals 'shocking' answer
A dentist has revealed which of four popular drinks stain teeth the most, and claimed he was 'shocked' by the results. Dr Miles Madison, a dentist based in Beverly Hills California, took four ...
eLife28d
Robust single nucleus RNA sequencing reveals depot-specific cell population dynamics in adipose tissue remodeling during obesity
Single nucleus RNA sequencing (snRNA-seq), an alternative to single cell RNA sequencing (scRNA-seq), encounters technical challenges in obtaining high-quality nuclei and RNA, persistently hindering ...
eLife1mon
The effects of 17α-estradiol treatment on endocrine system revealed by single-nucleus transcriptomic sequencing of hypothalamus
In this report, we utilized single-nucleus transcriptomic sequencing and performed supervised ... Formalin-fixed paraffin-embedded mouse testis sections of 5 µm thickness were used for HE Staining. At ...