Antibody–siRNA conjugates (ARCs) are a type of promising drug modalities for cancer therapy. However, initial reports of ARCs present the gene knockdown effect only in limited tissues (e.g., muscles) ...

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The variety of potentially useful dyes or haptenes available for fluorescent nucleic acid hybridization assays is far greater than what can be obtained from commercial sources 1,2. Since this ...

Scientists at The Wistar Institute have discovered how a key protein from the Epstein-Barr virus (EBV), EBNA-LP, ...

Advancements in manufacturing technologies is a key driver driving nucleic acid therapeutics CDMO market revenue growth.

Look inside a brain cell with Huntington's disease or ALS and you are likely to find RNA clumped together. These solid-like clusters, thought to be irreversible, can act as sponges that soak up ...

With more than 2,100 members, EMBO stands for excellence in the life sciences. It accepts outstanding researchers who are ...

By examining squid skin cells three-dimensionally, a University of California, Irvine–led team has unveiled the structures responsible for the creatures' ability to dynamically change their ...

Chinese scientists have developed a novel nanotherapy known as biomimetic extracellular vesicle spherical nucleic acids (BEV-SNAs), which has shown efficacy in treating idiopathic pulmonary fibrosis ...

Despite the pivotal role of nucleic acids in these networks, their contributions to allostery have largely been overlooked. To address this gap, we developed ComPASS, a large-scale computational ...

Correction for Smith et al., A twist grain boundary phase in aqueous solutions of the nucleic acid tetramer GTAC ...

Initially used as feed attractants, nucleotides (NT) and nucleic acids (NA) drew the attention of research and industrial communities as functional ingredients on account of their many features as ...