Linked to neurological disorders, repeat RNAs aggregate inside droplets but can be disassembled with an engineered piece of ...

Imagine if you could "print" a tiny skyscraper using DNA instead of steel. That’s what researchers at Columbia and Brookhaven ...

The variety of potentially useful dyes or haptenes available for fluorescent nucleic acid hybridization assays is far greater than what can be obtained from commercial sources 1,2. Since this ...

The Nucleic Acid Structure and Recognition Laboratory seeks to use RNA as the raw material for new kinds of gene regulators. These act by inhibiting or redirecting transcription factors. Taking a cue ...

The Nucleic Acid Structure and Recognition Lab is studying the concept that the exceptional stiffness of double-stranded DNA is related to DNA charge. This concept remains controversial even 60 years ...

The global demand for digital data is projected to be greater than the supply of semiconductor grade silicon in 2040 [1]. When combined with the need to archive information [2], nucleic acids are ...

DNA interstrand cross-links (ICLs) are cytotoxic products of common anticancer drugs and cellular metabolic processes, whose mechanism(s) of repair remains poorly understood. In this study, we show ...