DNA is fundamental to the biology of all life on Earth, but how many of us actually know what it is or what it's made of?

Peptide nucleic acids progress ... A line structure of a γ-PNA with a peptide backbone compared to a line structure of DNA with a phosphate ... the γ-PNA has hydroxymethyl groups hanging ...

In 1919, Russian biochemist, Phoebus Levene proposed that nucleic acids are made up of nucleotides, which are composed of one of the four bases – A (adenine), T (thymine), G (guanine) and C ...

OUR earlier work on the chemical action of X-rays on the nucleic acids in aqueous systems1 has led us to suggest that labile compounds, including labile phosphate esters, are formed on irradiation ...

The addition of a phosphate group ... inducing a conformational change or affecting its interactions with other proteins or nucleic acids. For example, in transcription, ...

Scientists visualize how a vital hepatitis C virus protein moves along its nucleic acid substrate ... A key component of this process is unidirectional movement of a phosphate group in the middle ...