Non-coding DNA provides vital genetic information to regulate this process of gene expression, ensuring that proteins are being produced just as they should be. And what about genome structure? Our ...

Research from the Garvan Institute of Medical Research indicates that non-coding DNA, which comprises 98% of our genome and was previously considered “junk,” may play a crucial role in cancer ...

DNA methylation at the promoter region of protein coding genes is one of the key components of epigenetic regulation. However, only limited number of examples that lncRNA regulate promoter methylation ...

Non-coding DNA variants contribute to acute lymphoblastic leukemia (ALL) chemotherapy resistance. St. Jude Children's Research Hospital scientists have identified specific DNA variants in the non ...

Non-coding DNA variants contribute to acute lymphoblastic leukemia (ALL) chemotherapy resistance. Explore new technology used in the St. Jude-led discovery.

UCSC researchers suggest that introns, a source of molecular complexity unique to eukaryotes, primarily originate from introners. The origins of introns, segments of non-coding DNA that must be ...

The genetic sequences under investigation included nearly 20,000 genes that encode information about how to make proteins, as well as 350,000 regulatory sequences composed of non-coding DNA, which ...

Recent literature witnesses plenty of examples where using chromosome conformation capture (3C)-based technologies successfully links non-coding variants to their target genes and prioritizes relevant ...

The non-random pattern in mutations between gene and non-gene regions of DNA suggests that there is a defensive mechanism in place to prevent potentially disastrous mutations.

In a new study, stem cell scientists at the Lund University, Sweden, explore the role of non-coding regions of the genome—previously deemed to be functionless “junk” DNA—and find humans ...

Hsieh’s previous work on prostate and bladder cancer had demonstrated that dysfunction in the protein-building process can promote cancer. More comprehensive DNA-sequencing studies, which included ...