Lymphocyte, monocyte, and basophil counts decrease in response to corticosteroid administration, while neutrophil counts ... complex translocates into the nucleus of the cell, where it attaches ...

TGF-β signaling pathway polarizes macrophages to the pro-tumorigenic M2 phenotype by increasing Snail, converts N1 neutrophils to an N2 phenotype by up-regulation of arginine, CCL2, CCL5, and ...

Strong evidence has been accumulated since the beginning of the COVID-19 pandemic that neutrophils play an important role in the pathophysiology, particularly in those with severe disease courses.

Nuclear pore complexes are the guardians of the human genome that is packaged into the nucleus of all cells. They form selective channels through the envelope of the nucleus and connect its ...

A new milestone in nuclear physics has been achieved with the direct observation of three different deformations in the atomic nucleus of lead-190 (190 Pb). These deformations, associated with ...

Novel therapeutic targets and approaches are needed to improve outcomes. Neutrophils are the most abundant immune cell and among the first responders to infection. Appropriate neutrophil responses are ...

Recent studies have demonstrated presence of an active neutrophil population in systemic circulation, featuring hypersegmented morphology, with high oxidative burst and functional plasticity in ...

Neutrophils are major players in innate immune system. Here, we aimed to explore the heterogeneity and pro-tumour mechanisms of neutrophils in PDAC. Design We analysed single-cell transcriptomes of ...