XtalPi has accrued a number of Big Pharma partners over the years, including Eli Lilly, which struck a $250 million deal in 2023 to use XtalPi’s tech to identify potential drug candidates that Lilly ...

Here the authors combine a deep generative model with structure-based drug design and prospectively validate functionally active, nanomolar, A 2A adenosine receptor ligands and solve their crystal ...

By learning electron-level information, Korean researchers have created an artificial intelligence (AI) tool that can ...

Researchers have found a new way to optimise the design molecular motors, bringing us one step closer to making synthetic molecular machines a reality ...

Each time a cell divides, a small section of each chromosome's protective cap—the telomere—is worn away. Most cells use an ...

Essentially, cereblon and its target proteins can change shape to form a complex with the cereblon, the target, and the ...

Cornell researchers have found a new and potentially more accurate way to see what proteins are doing inside living ...

Shandong University developed an advanced AI framework that predicts molecular properties in seconds with high accuracy and minimal computational ...

One class of functionally important RNA is repeating transcripts that cause disease through various mechanisms. For example, expanded CAG repeats can cause Huntington’s and other disease through ...

Physics articles from across Nature Portfolio Atom RSS Feed Physics is the search for and application of rules that can help us understand and predict the world around us. Central to physics are ...