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The Global Neurodegeneration Proteomics Consortium (GNPC) has published a series of research papers detailing their efforts ...
The molecular forces linking aging, cellular senescence, and the onset of these neurodegenerative conditions are not well understood.
The study, published in Molecular Neurodegeneration, examined age-related changes in genes and proteins of the retinas of nine strains of mice, mimicking the genetic variability found in humans.
In multiple sclerosis (MS), an alteration of neuronal metabolism caused by dysfunction of its proteasome, the cellular machinery responsible for recycling proteins, contributes to neurodegeneration in ...