At Texas A&M AgriLife Research, a new branch of brain science is blooming at the molecular scale—with nanoflowers.

More information: R. Blake Billmyre et al, Landscape of essential growth and fluconazole-resistance genes in the human fungal pathogen Cryptococcus neoformans, PLOS Biology (2025).

Furthermore, advancements in delivery systems have enhanced the bioavailability of these antioxidants, amplifying their therapeutic potential. This review delves into the dual pathological roles of ...

Defects in mitochondrial oxidative metabolism underlie many genetic disorders with limited treatment options. The incomplete annotation of mitochondrial proteins highlights the need for a ...

Recent studies implicate mitochondria playing a key role in the cellular response to copper depletion therapy; however, evidence has been indirect and downstream, and the initial target of chelation ...

Macrocyclic inhibitors have emerged as a privileged scaffold in medicinal chemistry, offering enhanced selectivity, stability, and pharmacokinetic profiles compared to their linear counterparts. Here, ...

The researchers identified the structure of this machine, the mitochondrial pyruvate carrier (MPC), and 50 years since its discovery, have shown how it operates like the lock on a canal to ...

New research challenges traditional views on ATP production and mitochondrial membrane potential, revealing that oxidative phosphorylation occurs in mitochondrial cristae and that sodium plays a ...

Western Blotting and Immunofluorescence Mitochondrial oxidative phosphorylation proteins in LA tissue lysates were analyzed by Western blotting. Fresh frozen myocardial LA tissue sections were used ...

A paper by scientists affiliated with the University of São Paulo highlights new discoveries regarding the mechanisms of oxidative phosphorylation involved in ATP production. Recent studies ...

Pro-inflammatory macrophage activation is a hallmark example of how mitochondria serve as signaling organelles. Oxidative phosphorylation sharply decreases upon classical macrophage activation, as ...

A lab has completed a six-year study to examine the virulence of 38 clinical isolates from various strains of Cryptococcus.