Donna Truscott want to solve the mystery of her missing grandfather. A DNA test took her search in a shocking direction.

Six-year-old Etan Patz disappeared while walking to a school bus stop in 1979. The publicity of the case led to a societal ...

Michigan has 594 people who are listed in a national missing persons database going back to 1958. The following are 12 ...

"48 Hours" goes inside the painstaking investigation through the eyes of those who have spent more than three decades trying ...

Philippa Langley, who helped unearth King Richard III's body from a parking lot in 2012, says that two young princes who ...

New evidence and witness claims suggest Amy Bradley might still be alive, reigniting hope and questions about her ...

Thursday marks nine years since 19-year-old Nahomi Rodriguez was last seen alive, opening a case that has yet to be solved.

Caroline Lowe keeps broadcaster Jodi Huisentruit close to the heart — especially in June. Every day of the month, she wears a necklace that says, “6/27/95,” the date ...

Sophie Reeder was 15 years old, and that video is the last known image of her on May 20th, 2017 — the day she disappeared.

Remains of Robert Long, missing since 2010, were recovered from a submerged car off Cedar Beach by volunteer groups.

A South Carolina mother and three of her children pleaded guilty in the murder case of a NC man who went missing two years ...