Traditional static algorithmic models often struggle to effectively capture the dynamic and evolving nature of consumer behavior in multichannel shopping environments, where consumers frequently ...

We have developed a hidden Markov model and optimization procedure for photon-based single-molecule FRET data, which takes into account the trace-dependent background intensities. This analysis ...

Enzymes catalyze chemical reactions in organisms—without which life would not be possible. Leveraging AlphaFold2 artificial ...

Enzymes catalyze chemical reactions in organisms - without which life would not be possible. Leveraging AlphaFold2 artificial ...

Representative structures for each of the four metastable states identified by our Markov State Model (MSM; S1-S4) and connected by the top one pathway from the pre-translocation state (S1) to the ...

A statistical model is autoregressive if it predicts future values based on past values (i.e., predicting future stock prices based on past performance).

A new model of TCP link state evolution In the settings of hidden Markov models (HMM) is introduced. A class of special Markov processes, which can be considered as generalization of the classic ...

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Using a novel metric for the cooperativity, we identify those residues leading to the least cooperative folding. The folding dynamics of the selected mutants are then directly characterized and the ...